地中海贫血 Mediterranean anemia 亦称海洋性贫血—thalassemia,是一组血红蛋白发生遗传性异常的疾病,表现为珠蛋白中的肽链有一种或一种以上合成减少、或不能合成而其他肽链代尝性合成增加,改变了正常血红蛋白的比例,或产生不正常的血红蛋白。随着分析技术的不断发展,对血红蛋白的分子结构基本已摸清。近年来发现异常的血红蛋白已超过200种之多。地中海贫血临床上往往有慢性增生性贫血,有些类型贫血十分严重,多伴有肝脾肿 Mediterranean anemia also known as marine anemia -thalassemia, is a group of hereditary genetic abnormalities of hemoglobin, the performance of the globin chain in one or more of the synthesis of reduced, or can not be synthesized and other peptide chain on behalf of Increased synthesis, changing the proportion of normal hemoglobin, or produce abnormal hemoglobin. With the continuous development of analytical techniques, the basic molecular structure of hemoglobin has been found out. In recent years, abnormal hemoglobin has been found more than 200 kinds. Thalassemia clinically often have chronic proliferative anemia, some types of anemia is very serious, often accompanied by hepatosplenomegaly