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目的了解不同方案治疗传染性软疣的临床疗效。方法将288例传染性软疣患者抽签随机分为六组,每组48例。分别采用电灼、刮除、冷冻、挑刺法、血管钳挤压、常见药物(以中药酊为例)方法治疗,治疗期2个月。比较分析各组治疗疗效、治疗过程中患者疼痛不良反应程度。结果总有效率比较:刮除组(93.8%)、挑刺组(93.8%)>电灼组(85.4%)>血管钳挤压组(75.0%)>冷冻组(66.7%)>中药酊药物组(64.6%),刮除组、挑刺组总有效率相比血管钳挤压组、冷冻组、中药酊药物组显著较高,差异有统计学意义(P<0.05);患者治疗过程中疼痛程度重度率电灼组(25.0%)>血管钳挤压组(20.8%)>挑刺法(18.8%)>刮除组(12.5%)>中药酊药物组(6.3%)>冷冻组(4.2%),冷冻组、中药酊药物患者疼痛程度重度率相比电灼组、血管钳挤压明显较低,差异有统计学意义(P<0.05)。结论刮除法、挑刺法治疗传染性软疣疗效显著,且患者疼痛不良反应程度适中,具有较高的临床价值,电灼法疗效显著,但疼痛感较重,适合成年人。
Objective To understand the clinical efficacy of different treatment programs for molluscum contagiosum. Methods 288 patients with molluscum contagiosum were randomized into six groups of 48 patients. Respectively using electrocautery, curettage, freezing, prick method, vascular clamp compression, common drugs (Chinese herbal tincture, for example) method of treatment, the treatment period of 2 months. Comparative analysis of the treatment effect of each group, the patient’s pain in the course of treatment of adverse reactions. Results The total effective rate: Scratch group (93.8%), prick-stabbing group (93.8%), electrocautery group (85.4%), vascular clamp crush group (75.0%), frozen group (66.7% (64.6%). The total effective rate of curettage group and curettage group was significantly higher than that of vascular clamp compression group, frozen group and traditional Chinese medicine tincture group (P <0.05). The pain rate (25.0%) in the severe rate group (20.8%) in the vascular clamp group (18.8%), the curettage group (12.5%), the Chinese medicine tincture group (6.3%) and the frozen group (4.2% (P <0.05). Compared with the electrocautery group, the severity of pain in the frozen group and the Chinese medicine tincture drug group was significantly lower than that of the electrocautery group (P <0.05). Conclusion curettage, prickle method for the treatment of molluscum contagiosum significant effect, and the degree of pain in patients with moderate, with high clinical value, electrocautery significant effect, but heavier pain, suitable for adults.