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目的评价胃乐胶囊对动物的毒副作用。方法将小白鼠分成两组，急性毒性试验组１２０只，长期毒性试验组９０只。急毒组给胃乐混悬液，实验用０．５％羧甲基纤维纳配成２０％、１５％的混悬液，以不同浓度按０．３ｍｌ／１０ｇ体重的容量进行灌胃，来观察胃乐对小白鼠的急性毒性反应。长毒组分为５组，其中４组（ｎ＝２０）分别给胃乐混悬液８０００ｍｇ·ｋｇ－１体重、４０００ｍｇ·ｋｇ－１体重、１０００ｍｇ·ｋｇ－１体重及生理盐水，另一组（ｎ＝１０）为胃乐混悬液大剂量附加组，剂量为８０００ｍｇ·ｋｇ－１体重，来观察胃乐对小白鼠的长期毒性反应。结果两组动物均未发现任何内脏损害。结论动物实验证明胃乐胶囊是一种使用安全的中成药。
Objective To evaluate the toxic and side effects of Weile capsule on animals. Methods The mice were divided into two groups: 120 acute toxicity test group and 90 long-term toxicity test group. Acute poisoning group to stomach music suspension, the experiment with 0.5% sodium carboxymethyl cellulose into 20%, 15% suspension, with different concentrations by 0.3ml / 10g body weight capacity for gavage to Observe the acute toxicity of WeiLe to mice. The long-toxic components were divided into 5 groups, 4 of which (n = 20) were given to the Weile suspension 8000mg · kg-1 body weight, 4000mg · kg-1 body weight, 1000mg · kg-1 body weight and saline, (N = 10) for the high dose of gastric suspension suspension group, the dose of 8000mg · kg-1 body weight to observe the long-term toxicity of Wei Le mice. Results No visceral damage was found in either group of animals. Conclusion Animal experiments prove that Weile capsule is a safe use of proprietary Chinese medicines.