论文部分内容阅读
目的探讨支气管激发试验(BPT)在慢性咳嗽及咳嗽变异型哮喘(CVA)诊断中的价值。方法对1155例慢性咳嗽患者进行乙酰甲胆碱支气管激发试验,检测其气道高反应性。结果1155例慢性咳嗽患者中,各年龄组肺功能参数比较无显著差异。BPT阳性584例,阴性571例,阳性率50.6%。确诊为CVA547例;其余37例BPT阳性慢性咳嗽患者中25例为感染后咳嗽,12例为慢性支气管炎。BPT诊断CVA的特异度为93.9%。小于30岁年龄组CVA比例最高,占慢性咳嗽68.8%;大于60岁的老年入CVA百分比最低,为23.5%。结论CVA是慢性咳嗽的主要病因,对不明原因的慢性咳嗽患者应及时进行BPT,有助于早期明确诊断并施以正确治疗。
Objective To investigate the value of bronchial provocation test (BPT) in the diagnosis of chronic cough and cough variant asthma (CVA). Methods A total of 1155 patients with chronic cough were subjected to methacholine bronchial provocation test to detect airway hyperresponsiveness. Results Among the 1155 patients with chronic cough, there was no significant difference in pulmonary function parameters among all age groups. 584 BPT positive, 571 negative, the positive rate of 50.6%. Of the remaining 37 BPT-positive chronic cough patients, 25 were coughing after infection and 12 were chronic bronchitis. The specificity of BPA in diagnosing CVA was 93.9%. The proportion of CVA in the group less than 30 years old was the highest, accounting for 68.8% of those with chronic cough. The percentage of CVA in the elderly over 60 years old was the lowest, 23.5%. Conclusion CVA is the main cause of chronic cough. BPT should be promptly carried out in patients with unexplained chronic cough, which is helpful for early diagnosis and correct treatment.