临床资料患者,女,66岁。因“活动后胸闷、气促5年,加重1个月”入院。患者于9年前行肾移植手术。查体:体温36.6℃,脉搏90次/min,呼吸20次/min,血压105/60 mm Hg。心界向左下方增大,心尖部可见抬举样搏动。胸骨右缘第2肋间闻及3/6级舒张中晚期叹息样杂音,周围血管征(+)。实验室检查:尿素氮7.8 mmol/L,尿酸157.0μmol/L,肌酐 Patients with clinical data, female, 66 years old. Because of “chest tightness after the event, shortness of breath 5 years, increased 1 month ” admission. The patient underwent kidney transplant nine years ago. Examination: body temperature 36.6 ℃, pulse 90 beats / min, breathing 20 beats / min, blood pressure 105/60 mm Hg. Heart left to increase the lower part of the apex can be seen lifting like beating. Sternal right intercostal scent 2 and 3/6 diastolic middle and late sigh like noise, peripheral vascular sign (+). Laboratory tests: urea nitrogen 7.8 mmol / L, uric acid 157.0μmol / L, creatinine