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目的观察每年给予中西医结合治疗对矽肺肺功能变化的影响。方法患者每年在广西壮族自治区职业病防治院住院1～3个月,住院期间给予低流量吸氧、无创双水平辅助通气治疗、静脉滴注中成药香丹、红花注射液、肺叶灌洗治疗,每年复查肺功能。结果 5年后FVC有上升趋势,但差异无统计学意义(P>0.05),FEV1较5年前无明显下降;矽肺晋期组、无晋期组5年前后FVC、FEV1变化不明显(P>0.05);5年前后肺功能损伤构成比差异无统计学意义(P>0.05)。结论中西医结合治疗可较好地改善矽肺患者肺部通气(血流比值),阻止肺功能损伤的发展。
Objective To observe the effect of the combination of traditional Chinese and western medicine on the changes of pulmonary function in silicosis every year. Methods Patients were hospitalized in Occupational Disease Prevention and Treatment Hospital of Guangxi Zhuang Autonomous Region every year for 1-3 months. During hospitalization, patients were given low-flow oxygen inhalation and noninvasive bi-level assisted ventilation. Intravenous infusion of proprietary Chinese medicines Xiangdan, safflower injection, Review lung function annually. Results After 5 years, FVC had an upward trend, but the difference was not statistically significant (P> 0.05), FEV1 had no significant decline compared with 5 years ago; FVC and FEV1 changed little after 5 years > 0. 05). There was no significant difference in the constituent ratio of pulmonary function after 5 years (P> 0.05). Conclusion The combination of TCM and WM can improve lung ventilation (blood flow ratio) in patients with silicosis, and prevent the development of lung injury.