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重组粒细胞集落刺激因子(GranulocyteColony Stimulating Factor)是一种单核巨噬细胞产生的细胞因子,有提高外周血中性粒细胞数的功能,人粒细胞集落刺激因子(G—CSF)的化学结构为含有神经氨酸的糖蛋白,分子量18～22kd,其基因编码位于17号染色体上,正常细胞产生的 G—CSF 由174个氨基酸组成,其主要来源于巨噬细胞、内皮细胞及纤维母细胞.G—CSF 可对靶细胞的特
Granulocyte Colony Stimulating Factor (Granulocyte Colony Stimulating Factor) is a kind of cytokine produced by mononuclear macrophages. It has the function of increasing the number of peripheral blood neutrophils, the chemical structure of human granulocyte colony-stimulating factor (G-CSF) Is a neuraminic glycoprotein with a molecular mass of 18-22kd. The gene encodes on chromosome 17, and G-CSF produced by normal cells is composed of 174 amino acids. It mainly comes from macrophages, endothelial cells and fibroblasts G-CSF target cells can be special