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弥散性血管内凝血(DIC)是急性白血病常见的严重并发症,也是患者死亡的重要原因之一。因此及时正确的诊断,对指导治疗及改善预后均具有重要的临床意义。血清纤维蛋白降解产物(FDP)的测定是诊断DIC的一项敏感指标,但部分未并发DIC的白血病患者FDP也可增高。为了进一步探讨急性白血病尤其是并发DIC时FDP的变化规律,我们用间接血凝免疫抑制试验观察了56例急性白血病患者的FDP变化,其中9例患者并发DIC,现报告如下。
Disseminated intravascular coagulation (DIC) is a common and serious complication of acute leukemia and one of the important causes of death in patients. Therefore, timely and correct diagnosis of the guiding treatment and improve the prognosis have important clinical significance. Determination of serum fibrin degradation products (FDP) is a sensitive indicator of DIC diagnosis, but some patients with leukemia without DIC can also be increased in FDP. To further investigate the changes of FDP in acute leukemia especially in patients with DIC, we observed the changes of FDP in 56 patients with acute leukemia using indirect hemagglutination immuno-suppression test. Nine of them were complicated with DIC, and the report is as follows.