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随着科学技术的发展和测试手段的改进 ,形态计量学得到了深化和发展 ,它已被广泛应用于临床病理研究工作 ,其中包括对非肿瘤病变与肿瘤病变、良性肿瘤与恶性肿瘤的鉴别诊断、对肿瘤恶性程度的分级、检查癌前病变及判断肿瘤的愈后及疗效等 ,其所研究的水平由组织、细胞水平向亚细胞和分子水平深入。近年来 ,有许多资料报道了用形态计量学和体视学的方法 ,研究大肠、胃、肝、肾、膀胱、子宫、甲状腺等器官的肿瘤 ,以找出反映病变特征的定量指标 ,来定量揭示正常和病变组织的形态结构、特征和机能间的关系。形态计量学具有客观性强 ,重复性好 ,能精确地以定量方式表达存在于组织中的各种信息等优点 ,因此对临床病理学研究有重要意义。
With the development of science and technology and the improvement of testing methods, morphometrics has been deepened and developed. It has been widely used in clinicopathological research, including the differential diagnosis of non-neoplastic lesions and tumor lesions, benign tumors and malignant tumors , Grade of malignant tumor, examination of precancerous lesions and judgment of prognosis and curative effect of the tumor. The level of the study is from the level of tissue and cell to subcellular level and molecular level. In recent years, there are many reports on the use of morphometry and stereology methods to study the large intestine, stomach, liver, kidney, bladder, uterus, thyroid and other organs of the tumor in order to find a quantitative indicator of disease characteristics to quantify Reveal the normal and diseased tissue morphology, characteristics and function of the relationship between. Morphometry has the advantages of strong objectivity, good repeatability, accurate and quantitative expression of various information existing in the tissue, and so is of great significance to clinical pathology research.