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目的 :探讨急性胰腺炎善得定治疗前后微循环的变化。方法 :采用MVIS— 2 0 2 0型全自动血液粘度计测定 46例急性水肿型胰腺炎 (AEP)患者善得定治疗前后血液流变学各项指标 (包括全血粘度、血浆粘度、还原粘度、红细胞压积、血沉、血沉方程K值、红细胞刚性指数 )。结果 :AEP患者在用善得定治疗后血液流变学各项指标均较治疗前明显下降(P <0 .0 5 ) ,尤其以血浆粘度、血沉方程K值下降明显 (P <0 .0 1 )。结论 :微循环测定可作为AEP临床疗效观察指标 ,善得定治疗AEP ,可迅速改善胰腺局部及全身微循环障碍
Objective: To investigate the changes of microcirculation before and after treatment of acute pancreatitis. Methods: The indexes of hemorheology (including whole blood viscosity, plasma viscosity, reducing viscosity and blood viscosity) of 46 patients with acute edematous pancreatitis (AEP) before and after treatment were measured by MVIS-20020 automatic blood viscometer , Hematocrit, erythrocyte sedimentation rate, erythrocyte sedimentation rate K value, erythrocyte rigidity index). Results: The indexes of hemorrheology in AEP patients were significantly decreased (P <0.05), especially in plasma viscosity and erythrocyte sedimentation rate K values (P <0. 0) 1 ). Conclusion: Microcirculation can be used as a clinical indicator of AEP, and Sedative treatment of AEP can rapidly improve local and systemic pancreatic microcirculation