,Adult neurogenesis in Provence: Where history meets science

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In the idyllic medieval village of Sehac situated in the heart of old Provence,in September 2015 Workshop organizers Michael Valenzuela and Mirjana Maletic-Savatic brought together scientists around the globe to participate in the third biannual workshop,this time on adult neurogenesis.The workshop covered diverse aspects of neurogenesis,both in animal and human,presented in this Special Issue of Frontiers in Biology as a selection of articles that highlight new discoveries and challenges along the way.Since its discovery in 1962 and establishment in the 1990s,adult neurogenesis has captured the mind of scientists,clinicians,and the public alike.Adult neurogenesis promises new avenues for brain regeneration and the treatment of a wide variety of neurological and mental disorders.Underlying this is a rapidly expanding understanding of neural stem cells and precursors that are the biological basis for neurogenesis.These cells have been envisioned as the source of donor cells for transplantation,as vectors for gene therapy and as endogenous targets for pharmacological upregulation.
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