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应用粘液组织化学及ＡＢＣ酶标亲合组织化学技术对１１７例胃癌的粘液分泌及菜豆凝集素（ＰＨＡ）受体的表达进行了观察。结果：胃癌组织的ＰＨＡ受体表达率与癌的组织学类型无关，而与胃癌的组织化学分型有关，其中肠型胃癌的ＰＨＡ受体表达率（９５．１％，５８／６１）显著高于胃型胃癌（５７．１％，１６／２８）（Ｐ＜０．０１），肠型胃癌的硫酸粘液检出率（９３．４％，５７／６１）显著高于胃型胃癌（无检出）（Ｐ＜０．０１）。肠型胃癌的肠化检出率（８６．９％，５３／６１）显著高于胃型胃癌（３５．７％，１０／２８）（Ｐ＜０．０１），肠型胃癌旁肠化ＰＨＡ受体表达率（８１．１％，４３／５３）显著高于胃型胃癌旁肠化（４０．０％，４／１０）（Ｐ＜０．０５）。提示：肠型胃癌起源于肠化粘膜，特别是柱状细胞分泌硫酸粘液的肠化粘膜；而胃型胃癌起源于胃固有粘膜。
Mucus histochemistry and ABC enzyme-labeled affinity histochemistry were used to observe the mucus secretion of gastric cancer and the expression of PHA receptor. RESULTS: The expression rate of PHA receptor in gastric cancer tissues was not associated with the histological type of cancer, but related to the histochemical typing of gastric cancer. The expression rate of PHA receptor in intestinal type gastric cancer was significantly higher (95.1%, 58/61). Gastric gastric cancer (57.1%, 16/28) (P<0.01). The detection rate of sulphuric acid mucus in intestinal type gastric cancer (93.4%, 57/61) was significantly higher than gastric gastric cancer (no test Out) (P<0.01). The detection rate of intestinal metastasis in intestinal type gastric cancer (86.9%, 53/61) was significantly higher than that in gastric type gastric cancer (35.7%, 10/28) (P<0.01). Paragastric intestinal metaplasia PHA The rate of receptor expression (81.1%, 43/53) was significantly higher than that of gastric type gastric cancer (40.0%, 4/10) (P<0.05). Tip: Gastrointestinal gastric cancer originates from intestinal mucosal membranes, especially intestinal mucosa that secrete sulfated mucus from gastric mucosa. Gastric gastric cancer originates from the intrinsic mucosa of the stomach.