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本研究以光栅为刺激所同时产生的图形视觉诱发电位（Ｐ－ＶＥＰ）和图形视网膜电图（Ｐ－ＥＲＧ）为指标，测定了单眼视剥夺和反缝的新生幼猫个体在发育不同阶段的空间频率调谐曲线，并与同龄正常猫、成年正常猫进行了比较研究。结果显示，在０．１２—１．５ｃ／ｄ空间频率范围内，正常幼猫单独刺激其左眼和右眼所驱动的Ｐ－ＶＥＰ振幅相近，但都明显地比双眼驱动的为小。在单眼剥夺的幼猫，由剥夺眼所驱动的Ｐ－ＶＥＰ振幅大幅度下降，健康眼所驱动的Ｐ－ＶＥＰ则大幅度上升，两者相差悬殊，同时双眼驱动的Ｐ－ＶＥＰ振幅介于两者之间。在反缝的幼猫，原视剥夺眼驱动的Ｐ－ＶＥＰ有不同程度的恢复，反缝眼的Ｐ－ＶＥＰ振幅比反缝前降低，两者趋于接近，双眼驱动的Ｐ－ＶＥＰ振幅最大。在单眼缝合前后的成年猫则不存在上述Ｐ－ＶＥＰ空间频率调谐曲线的位移。Ｐ－ＥＲＧ的测定表明，在发育早期双眼视网膜间不存在功能上的竞争。本研究支持Ｈｕｂｅｌ和Ｗｉｅｓｅｌ提出的视皮层细胞眼优势发育中的竞争机制和漂移学说，为用Ｐ－ＶＥＰ为指标于临床儿童（尤其婴儿）弱视早期诊断和预后提供了科学依据。
In this study, the visual evoked potentials (P-VEPs) and the electroretinogram (P-ERG) were simultaneously generated by the grating as the stimulus, and the effects of monocular deprivation and anti-sewn neonatal kittens at different developmental stages Spatial frequency tuning curve, and compared with normal cats of the same age and adult normal cats. The results showed that in the spatial frequency range of 0.12-1.5c / d, normal pulsed stimulation of P-VEP in left and right eyes stimulated the normal amplitude, but both of them were obviously smaller than that of binocular driving. In the monocular deprived kittens, the amplitude of P-VEP driven by deprivation eyes dropped significantly, the P-VEP driven by healthy eyes increased significantly, the difference between the two was significant, and the amplitude of binocular-driven P-VEP was between two Between. In the reverse-sewed kittens, the P-VEP with deprivation of the original eye deprived to some extent, and the amplitude of P-VEP in the reverse seamed eye was lower than that before the reverse seams, and the two tended to be close, and the amplitude of binocular-driven P-VEP was the largest . Adult cats before and after monocular sutures do not exhibit the displacement of the P-VEP spatial frequency tuning curve. The P-ERG assay shows that there is no functional competition between binocular retina early in development. This study supports the competitive mechanism and drift theory proposed by Hubel and Wiesel in the dominance of visual cortex cells and provides a scientific basis for the early diagnosis and prognosis of amblyopia in clinical children (especially infants) using P-VEP as an indicator.