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将４０例白血病患儿随机分为两组，每组各２０例。分别以不同的速度静脉注射柔红霉素，Ａ组注射速度为１ｍｌ／ｍｉｎ，Ｂ组为３ｍｌ／ｍｉｎ，观察两组患者心肌酶谱、心脏血流参数的变化及血管损害情况。结果显示：注射前后心肌酶谱及心脏血流参数组内配对ｔ检验有差异（Ｐ＜０．０１），而组间比较无差异（Ｐ＞０．０５），两组静脉炎发生例次也有差异（Ｐ＜０．０５），Ａ组明显高于Ｂ组。提示快速静脉注射柔红霉素既能减少静脉炎的发生，又不会加重心脏的毒性作用，对白血病患者的临床用药具有参考价值。
Forty children with leukemia were randomly divided into two groups, each with 20 cases. Intravenous injection of daunorubicin was performed at different rates. The injection rate was 1 ml/min in group A and 3 ml/min in group B. Changes in myocardial enzymes, cardiac blood flow parameters, and vascular lesions were observed in both groups. The results showed that the paired t-test showed a difference between the myocardial zymogram and the cardiac blood flow parameters before and after injection (P<0.01), but there was no difference between the two groups (P>0.05). There were also cases of phlebitis in both groups. Differences (P<0.05) were significantly higher in group A than in group B. This suggests that rapid intravenous infusion of daunorubicin not only reduces the occurrence of phlebitis, but also does not aggravate the toxic effects of the heart. It has a reference value for the clinical use of leukemia patients.