论文部分内容阅读
10例急性甲醇中毒病人分别于摄入甲醇后1～48小时收住院。6男4女,年龄为21～38岁。入院后分别测定酸硷平衡和电解质状况,血液甲醇及甲酸含量。检查发现,他们有酸中毒和低血钾症等甲醇中毒表现。血中硷缺失和CO_2总量与甲酸盐浓度显著相关(P<0.05),而与甲醇浓度不相关,看来甲酸盐蓄积是甲醇中毒早期酸中毒的主要原因。经给予硷性药物和乙醇以及血透析治疗,5例痊愈,4例有明显的眼损害后遗症,1例于入院后50小时死于心搏骤停。上述遗有严重后遗症的4例和死亡的1例患者,均在摄入甲醇
10 cases of acute methanol poisoning patients were hospitalized 1 to 48 hours after ingestion of methanol. 6 men and 4 women, aged 21 to 38 years old. After admission were measured acid-base balance and electrolyte status, blood methanol and formic acid content. Check found that they have acidosis and hypokalemia and other methanol poisoning performance. There was a significant correlation between blood alkaline deficit and CO 2 total amount and formate concentration (P <0.05), but not with methanol concentration. It seems that formate accumulation is the main reason for early acidosis in methanol poisoning. After given alkaline drugs and ethanol and hemodialysis treatment, 5 cases recovered, 4 cases had obvious eye damage sequelae, 1 case died of cardiac arrest 50 hours after admission. Four of the above serious sequelae and one patient who died were consuming methanol