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红细胞是吡多醇(维生素B_6)转化为吡多醛最活跃的场所。其转变的速度称为转化率。本文研究了β-海洋性贫血(简称β-海)患者红细胞吡多醇代谢及其转化率慢的原因。研究对象与结果(一)病人与对照组的红细胞吡多醇转化率(1)对照组:76名健康人,年龄17～65岁,转化率范围很广。其中5名(7%)转化率明显慢于另外71人。(2)杂合子β-海(海洋性贫血特征);107人,慢转者占63 %,极慢者占11% (3)轻型纯合子β-海;13人,本组中仅一例为
Erythrocytes are the most active sites for the conversion of pyridoxine (vitamin B_6) to pyridoxal. The rate of change is called conversion rate. In this paper, β-thalassemia (β-sea) erythrocyte erythropoiesis metabolism and the reasons for the slow conversion rate. Subjects and Results (a) Patient and control group, erythrocyte conversion of pyriol (1) control group: 76 healthy people, aged 17 to 65 years old, a wide range of conversion rates. Five of them (7%) were significantly slower than the other 71 people. (2) Heterozygous β-sea (characteristic of marine anemia); 107 people, 63% of slow-moving persons and 11% of patients with extremely slow rate (3) Light homozygote β-sea;