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正常成年人群的乙型肝炎疫苗(简称乙肝疫苗)的预防接种,迄今仍没有统一的方案及接种对象的选择标准。为此,我们对575名健康成人血清乙型肝炎病毒标志(HBV-M)的普查资料进行分析,并对成年人群乙肝疫苗的应用价值进行了探讨。材料与方法一、调查对象 575名检查对象为南京某自动化研究所职工,年龄20～81岁,其中3人超过60岁,男性344名,占59.8%,女性231名,占40.2%,均无乙肝疫苗接种史,除1例有甲型肝炎病史外,余均无明确的肝炎病史及输血史。二、血清HBV-M检测 HBV-M包括HBsAg,抗-HBs,HBeAg,抗-HBe,抗-HBc五项,均采用ELISA法检测。药盒购自军事医学科学院生物技术开发公司,结果判定及操作步骤均按说明书进行。
Normal adult population of hepatitis B vaccine (hepatitis B vaccine for vaccination, so far there is no uniform program and selection criteria for vaccination. To this end, we analyzed the census data of 575 healthy adults with hepatitis B virus (HBV-M) markers and explored the application value of hepatitis B vaccine in adults. MATERIALS AND METHODS A. Subjects The 575 subjects were workers of an automation institute in Nanjing, aged 20-81 years, of whom 3 were over 60 years old, 344 were male, accounting for 59.8% and 231 were female, accounting for 40.2% Hepatitis B vaccination history, in addition to a case of hepatitis A history, I have no clear history of hepatitis and blood transfusion history. Second, the serum HBV-M detection of HBV-M including HBsAg, anti-HBs, HBeAg, anti-HBe, anti-HBc five, were detected by ELISA. Kit purchased from the Military Academy of Medical Sciences Biotechnology Development Corporation, the results of the decision and steps are carried out according to instructions.