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目的探讨BiPAP治疗COPD合并II型呼吸衰竭的疗效。方法选择60例COPD合并II型呼吸衰竭患者,将患者随机分为对照组和观察组,每组30例。对照组采用气管内插管治疗,观察组采用双水平气道正压无创通气(BiPAP)治疗,观察两组患者治疗前、48h后的动脉血气、辅助呼吸肌动用情况和临床疗效。结果观察组动脉血气和疗效较对照组显著改善,P<0.05;观察组辅助呼吸肌动用评分明显低于对照组,P<0.05。结论 BiPAP治疗COPD合并II型呼吸衰竭的疗效好。
Objective To investigate the efficacy of BiPAP in treating COPD with type II respiratory failure. Methods Sixty COPD patients with type II respiratory failure were selected. The patients were randomly divided into control group and observation group, 30 cases in each group. The control group was treated with endotracheal intubation. The observation group was treated with bi-level positive airway pressure noninvasive ventilation (BiPAP). Arterial blood gas, assisted breathing muscle activity and clinical efficacy were observed before and 48h after treatment. Results The arterial blood gas and the curative effect in the observation group were significantly improved compared with the control group (P <0.05). The score of the auxiliary respiratory muscle in the observation group was significantly lower than that in the control group (P <0.05). Conclusions BiPAP is effective in treating COPD with type II respiratory failure.