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本文报告13例临床诊断为病毒性脑炎患儿应用人α-干扰素治疗。其中发病在3天内表现为高颅压、癫痫、瘫痪和精神障碍者12例,乙型脑炎呈去皮层状态,病程已45天1例。人α-干扰素每支2ml,每1ml含干扰素8000～12000U,每日肌注一次,连续注射3次者8例,6次者5例。结果体温在给药后12～48h降至38℃以下,病情改善和恢复较快,3周内达到临床治愈标准。提示人α-干扰素治疗病毒性脑炎有效,值得进一步探讨。
This article reports the clinical diagnosis of 13 cases of viral encephalitis in children with human interferon alpha treatment. Including onset of intracranial hypertension in 3 days, epilepsy, paralysis and mental disorders in 12 cases, encephalitis was cortical state, the course of 45 days in 1 case. Interferon alpha 2ml each, containing interferon per 1ml 8000 ~ 12000U, intramuscular injection once a day, three consecutive injections of 8 cases, 6 times in 5 cases. Results The body temperature decreased to less than 38 ℃ after 12 ~ 48h after administration, the condition improved and recovered quickly, and reached the clinical cure standard within 3 weeks. Prompt human interferon αeffective treatment of viral encephalitis, it is worth further study.