家族性高胆固醇血症的发现证明了高脂血症是动脉硬化发展中重要的危险因素,此病的纯合子罕有能活到20岁者,大多数在十多岁死亡。患病儿童在3—5岁就能发展为严重的动脉硬化,并可造成心肌梗塞.近年国际卫生研究所的研究更确切地证明了血浆胆固醇浓度降低可降低发生冠心病的危险。进一步强调高脂血症作为冠心病危险因素的 The discovery of familial hypercholesterolemia proves that hyperlipidemia is an important risk factor for the development of atherosclerosis. Homozygotes for this disease rarely live to 20 years of age, and most die in their teens. Ill children develop severe arteriosclerosis at 3-5 years of age and can cause myocardial infarction.Recent studies by the International Institute of Health in recent years have demonstrated more accurately that reduced plasma cholesterol levels reduce the risk of coronary heart disease. Further emphasis on hyperlipidemia as a risk factor for coronary heart disease