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肿瘤多向耐药基因是目前肿瘤药物治疗及手术后化疗防治复发失败的重要影响因素。本文意在总结近年来，对多向耐药基因与其表达蛋白P－GP170研究的分子生物学特性、在临床各种肿瘤中的检测以及其逆转方法的研究和临床应用，从而进一步探讨临床肿瘤治疗中存在的问题和今后研究的方向。
The multidrug resistance gene in tumors is an important influencing factor for the prevention and treatment of relapse failure after oncological drug therapy and postoperative chemotherapy. The purpose of this article is to summarize the molecular biological characteristics of multi-drug resistance gene and its expressed protein P-GP170 in recent years, and to study and clinically apply the detection and reversal methods of multidrug resistance genes and their reversal methods to further explore clinical tumor treatment. Problems and future research directions.