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莽草酸作为抗禽流感病毒药物的合成原料已逐渐被开发利用,莽草酸和其相关的衍生物具有重要的医学价值。首先,莽草酸是抗病毒和抗癌的重要组成部分;其次,它可以抑制血小板聚集,具有明显的抗血栓作用;再次,莽草酸还可发挥良好的抗炎镇痛作用。而莽草酸的一些衍生物对于恶性肿瘤具有很强的抑制作用。基于莽草酸的科学价值,现对莽草酸的一般理化性质,来源及莽草酸和其衍生物在医学方面作用的最新进展进行综述,为进一步研发和利用莽草酸资源提供参考。
Shikimic acid has been gradually developed as a synthetic raw material for anti-avian influenza virus drugs, and shikimic acid and its related derivatives have important medical value. First, shikimic acid is an important part of antiviral and anti-cancer drugs. Second, it inhibits platelet aggregation and has an obvious antithrombotic effect. Second, shikimic acid can also exert good anti-inflammatory and analgesic effects. Some of the shikimic acid derivatives have a strong inhibitory effect on malignant tumors. Based on the scientific value of shikimic acid, the general physical and chemical properties and sources of shikimic acid and the recent advances in the role of shikimic acid and its derivatives in medicine are summarized, which provide references for further research and utilization of shikimic acid.