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目的:探讨和评价部分脾栓塞术(PSE)治疗肝硬化脾功能亢进的临床应用价值。方法:采用Seldinger技术对28例乙肝后肝硬化伴脾功能亢进患者用高压消毒明胶海绵颗粒共进行31次PSE。结果:28例手术中27例获得成功,栓塞范围为30％-60％,25位患者术后1周以内、1-2周及2周以上WBC和PLT均有不同程度的上升(P<0.01),临床有效率为92.6％。手术前后肝功能变化不大。全部病例均未发生严重并发症。结论:部分脾栓塞术对治疗肝硬化脾亢有明显疗效,可替代脾切除术。对肝功能的改善,近期疗效不明显。
Objective: To investigate and evaluate the clinical value of partial splenic embolization (PSE) in the treatment of liver cirrhosis and hypersplenism. Methods: A total of 28 patients with hepatitis B cirrhosis complicated with hypersplenism were treated with high-pressure sterilized gelatin sponge particles for 31 times with Seldinger technique. Results: Twenty-seven cases were successfully treated with 30% -60% of embolization. The WBC and PLT of 25 patients within 1 week, 1-2 weeks and 2 weeks after operation increased to some extent (P <0.01) ), The clinical effective rate was 92.6%. Liver function changes before and after surgery. No serious complications occurred in all cases. Conclusion: Some splenic embolization has a significant effect on the treatment of hypersplenism in liver cirrhosis, which can replace splenectomy. The improvement of liver function, the recent effect is not obvious.