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本文对56例过敏性哮喘患儿用粉尘螨注射液作了脱敏治疗,认为疗效肯定,总有效率为87.5%.其脱敏疗效与患儿年龄以及病情轻重无关(P>0.05),与脱敏次数有关(P<0.01).作者还将患儿分为螨过敏性哮喘和非螨过敏性哮喘两组,均用螨脱敏治疗,观察两组疗效,无显著性差别(P>0.05).认为可能与免疫治疗中产生的非特异性阻断抗体有关.大多数患儿经脱敏治疗后IgG 水平有所上升,而IgA、IgM 水平治疗前后变化不大.作者认为,IgG 的上升可认为是临床治疗后重要的免疫学改变,可成为临床判断疗效的指标.
In this paper, 56 cases of allergic asthma children with dust mite injection for desensitization treatment, that efficacy is positive, the total effective rate was 87.5% .The desensitization efficacy has nothing to do with children age and severity of illness (P> 0.05), and The number of desensitization (P <0.01) .The children were also divided into mites allergic asthma and non-mite allergic asthma two groups were treated with demetonation mites, the two groups observed efficacy, no significant difference (P> 0.05 ) That may be associated with immunosuppressive non-specific blocking antibodies related to the majority of children after desensitization treatment IgG levels increased, while the IgA, IgM levels before and after treatment did not change much.The author believes that the increase of IgG may be Considered to be an important immunological change after clinical treatment, which may become an index of clinical judgment and curative effect.