Wip1是人们新近发现的一种原癌基因,已经证明它在多种肿瘤中存在高表达,能够促进肿瘤生长,并且与患者预后密切相关。许多研究表明,以Wip1为靶点的基因治疗,能够在体内外抑制肿瘤细胞增殖,延缓肿瘤生长。Wip1有望成为治疗恶性肿瘤的新靶点。 Wip1 is a recently discovered proto-oncogene that has been shown to be overexpressed in a variety of tumors and to promote tumor growth and is closely related to patient prognosis. Many studies show that gene therapy targeting Wip1 can inhibit tumor cell proliferation and delay tumor growth both in vitro and in vivo. Wip1 is expected to become a new target for the treatment of malignant tumors.