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猪2型圆环病毒是引起猪圆环病毒病,如断奶仔猪多系统衰竭综合征、猪呼吸疾病综合征、猪皮肤和肾病综合征等的重要病原体。该病毒可诱发多种病毒和/或细菌的混合感染和继发感染,给养猪业造成巨大的经济损失。近年来,国内外研究者都在致力于猪2型圆环病毒疫苗的研究开发。到目前为止,部分疫苗已在临床试验中取得成功,有的已投入应用,其他候选疫苗也正在积极研究过程中。本文就近年来国内外各类猪2型圆环病毒疫苗的研究进展及存在的问题和可能的解决办法作一综述。
Porcine circovirus type 2 is an important causative agent that causes porcine circovirus disease such as multiple system failure syndrome in weaned piglets, swine respiratory disease syndrome, pig skin and nephrotic syndrome. The virus can induce mixed infection and secondary infection of a variety of viruses and / or bacteria, causing huge economic losses to the pig breeding industry. In recent years, researchers at home and abroad are committed to the research and development of porcine circovirus type 2 vaccine. So far, some vaccines have been successful in clinical trials, others have been put into use and other candidate vaccines are being actively researched. This review summarizes the research progress, existing problems and possible solutions of various types of porcine circovirus type 2 vaccines at home and abroad in recent years.