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本文作者报道了14价肺炎球菌苗苗对扁桃体-咽炎和上呼吸道菌群的影响。共405名半岁～5岁幼儿参加了试验。405名幼儿分为两组,第1组半岁～2岁,44名接种菌苗,48名接受生理盐水作为对照;第2组2～5岁,154名接种菌苗,159名接受生理盐水作为对照。结果表明,2岁内的婴儿中,接种组急性扁桃体炎的发病率明显高于对照组(P<0.01),2岁以上的幼儿中,急性扁桃体炎和上呼吸道感染的发病率,接种组明显低于对照组(P<0.01);接种组无症状A群溶血性链球苗带菌率明显上升(P<0.01),相反接种
The authors report the effect of 14-valent pneumococcal vaccine on tonsillar pharyngitis and upper respiratory flora. A total of 405 semi-aged to 5-year-old children participated in the trial. 405 children were divided into two groups, the first group of semi-aged to 2 years old, 44 vaccinated bacterins, 48 received saline as a control; the second group of 2 to 5 years old, 154 vaccinated vaccine, 159 received saline as comparison. The results showed that the incidence of acute tonsillitis in vaccination group was significantly higher than that in control group (P <0.01). The incidence of acute tonsillitis and upper respiratory tract infection in children over 2 years old was significantly higher than that in inoculation group (P <0.01). The inoculation group showed a significant increase in the carrier rate of streptococcal hemolytic streptococcus (P <0.01)