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目的 为体外受精和胚胎移植临床中选择移植胚胎提供参考指标。方法 回顾性分析在本中心行IVF -ET治疗并在取卵后第 2天移植胚胎的 1 2 0个妊娠周期共 4 53个移植胚胎的资料。结果 1 2 0个治疗周期中单胎 75例 ,双胎 33例 ,3胎 1 0例 ,4胎以及 5胎各 1例。 4细胞期胚胎所占的比例从单胎的 4 7 3%增至双胎的 53 2 %和 3胎的 72 5% ,妊娠胎数随移植胚胎中≥ 4细胞期胚胎的增多而明显增加 ( χ2 =1 0 81 3,P <0 0 5)。结论 形态学可以作为选择移植胚胎的参考指标之一 ,但如何在保证妊娠率的同时减少移植胚胎的数目而降低多胎妊娠率还需进一步的前瞻性研究。
Objective To provide a reference index for selecting embryos for transplantation in vitro fertilization and embryo transfer. Methods The data of 4 53 embryos transferred in IVF-ET treatment and transplanted on the 2nd day after ovulation in 120 pregnancy cycles were retrospectively analyzed. Results Totally 75 cases of singleton, 33 cases of twins, 10 cases of 3 pregnancies, 1 case of 4-fetuses and 1 case of 5-fetuses were enrolled in the 120 cycles. The proportion of 4-cell embryos increased from 47.3% of singletons to 53.2% of twin births and 72.5% of 3-birth embryos. The number of gestational births was significantly increased with the increase of ≥4-cell embryos in transplanted embryos χ2 = 1 0 81 3, P <0 0 5). Conclusion Morphology can be used as one of the reference indexes for selecting embryos for transplantation. However, further prospective studies on how to reduce the number of embryos by reducing the number of transplanted embryos while ensuring the pregnancy rate are needed.