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目前国内外用于冷烫的卷发剂仍然以巯基醋酸铵（ＴＧＡ）为主要成分。本文介绍钡—钠合成法及多硫化钠—锌粉还原法制造的巯基醋酸铵的化学原理。冷烫液配方的调整对头发形态的影响，当ＴＧＡ小于２０％对头发无影响，含量超过５％带来难闻的硫化氢的气味，调节配方中羟基酸、有机胺和乙醇三者比例，阻止硫化氢产生。在配方中加入１～２％的糖，既使卷发过程缩短，又是良好护发剂；ＰＨ值升高，头发弯曲度增高，超过９．５氨所带来的刺激性增加，ＰＨ值数适的范围９．４～９．５；较适用的温度在４５～６０℃，卷发时间３０～４０ｍｉｎ。经改进后，克服了需用定型液的缺点。与通用的冷烫剂比较，用改进配方配制的冷烫剂不但能有效地保持头发的卷曲和柔软，而且也是很好的头发保护剂。
At present, domestic and foreign curling agents for cold iron are still based on mercaptoacetic acid ammonium (TGA) as the main component. This article describes the chemical principles of barium - sodium synthesis and sodium polysulfide - zinc reduction of mercapto-ammonium acetate manufactured by the chemical principles. Cold hot liquid formula to adjust the shape of the hair, when the TGA less than 20% of the hair no effect, more than 5% of the odor caused by the odor of hydrogen sulfide, adjust the formula hydroxy acids, organic amine and ethanol ratio of the three, to prevent Hydrogen sulfide production. Adding 1 ~ 2% sugar in the formula, even if the curly hair shorten the process, but also a good hair conditioner; PH value increases, the hair bending increased, more than 9.5 ammonia caused by increased irritation, PH value The suitable range of 9.4 ~ 9.5; more suitable temperature at 45 ~ 60 ℃, curling time 30 ~ 40min. After the improvement, to overcome the shortcomings of the need to use stereotypes. Compared with the common cold-reducing agent, the cold-reducing agent formulated with the improved formula not only can effectively keep the hair curly and soft, but also is a good hair protective agent.