作者对18～40岁无伤寒病史的志愿者,进行了两次伤寒Vi荚膜多糖菌苗免疫,采用双盲法评价临床表现和血清学应答.菌苗由法国梅里厄研究所提供.冻干菌苗含Vi多糖25μg,使用前,用等渗缓冲溶液稀释.液体菌苗是等渗缓冲溶液中含Vi荚膜多糖25μg,菌苗或安慰剂(生理盐水)每次肌肉注射0.5ml.初次免疫时,志愿者随机分组接受冻干 The author of 18 to 40-year-old history of non-typhoid fever volunteers, twice vaccination of the Typhoid Vi capsular polysaccharide, double-blind evaluation of clinical manifestations and serological response. Vaccine by the French Merriaux Institute. The vaccine containing Vi 25μg, before use, diluted with an isotonic buffer solution of liquid vaccine is isotonic buffer solution containing Vi capsular polysaccharide 25μg, vaccine or placebo (saline) intramuscular injection of 0.5ml. At the time of immunization, volunteers were randomly assigned to receive lyophilization