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在造血组织增殖性疾病的临床上,了解肝脏病理改变,有重要的实际意义。作者观察分析1,124例白血病和淋巴瘤病人,以临床、肝生物化学、HB抗原、肝同位素扫描、肝活检等资料为诊断依据,发现1,124例中有肝脏损害者占93.5%,依其临床发病机制,将这些肝脏损害分为四大类型: (1)特异性造血组织增殖性肝损害(52.3%):肝内常见浸润或结节状增殖性损害。急性白血病和晚期慢性白血病以浸润为主,结节状病变常见于淋巴肉芽肿及淋巴瘤。胆管可由于肿瘤细胞增殖阻塞形成郁疸性肝炎,此时可有黄疸。
In the clinical hematopoietic tissue proliferative diseases, to understand the pathological changes in the liver, has important practical significance. The authors observed 1,124 cases of leukemia and lymphoma patients, clinical, liver biochemistry, HB antigen, liver isotope scan, liver biopsy and other data for the diagnosis based on the found that 1,124 cases of liver damage accounted for 93.5%, according to its clinical pathogenesis , These liver damage is divided into four types: (1) specific hematopoietic tissue proliferative liver damage (52.3%): common intrahepatic infiltration or nodular proliferative damage. Acute leukemia and advanced chronic leukemia infiltration, nodular lesions common in lymphogranuloma and lymphoma. Bile duct due to tumor cell proliferation and obstruction to form jaundice hepatitis, this time may have jaundice.