甲氰咪胍(以下简称甲咪)是H_2-受体阻滞剂,临床普遍用于消化道溃疡和出血的治疗。但其神经精神系统副反应(简称NM副反应)近年来屡有报道。我院近三年应用甲咪治疗消化道出血208例,发现NM副反应12例,报告如下。 临床资料 12例中,男9例,女3例。年龄16～82岁,平均56岁,>60岁者7例。肝硬化并消化道出血7例,慢性肾衰并消化道出血2例,消化道溃疡3例。静脉或并用口服0.4～1.6克/日者11 Cimetidine (hereinafter referred to as methyl microphone) is H 2 -receptor blockers, clinically common for the treatment of peptic ulcer and bleeding. However, its neuropsychiatric side effects (referred to as NM side effects) have been reported in recent years. Nearly three years my hospital application of methylphenidate treatment of 208 cases of gastrointestinal bleeding and found that 12 cases of NM side effects, the report is as follows. Clinical data of 12 cases, 9 males and 3 females. Aged 16 to 82 years old, average 56 years old,> 60 years old in 7 cases. Cirrhosis and gastrointestinal bleeding in 7 cases, chronic renal failure and gastrointestinal bleeding in 2 cases, 3 cases of peptic ulcer. Intravenous or oral 0.4 ~ 1.6 g / day 11