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目的研究胆石症伴胆汁反流患者与慢性胃炎、消化性溃疡等疾病的关系。方法观察530例胆石症患者和100例无胆石症的消化不良者胃、十二指肠的内镜及组织学变化。结果胆石症组伴发胃、十二指肠疾病183例(34.5%),其中胆汁反流性胃炎98例(53.6%),消化性溃疡46例(25.1%);而无胆石症的消化不良组分别为9%和18%。慢性胃炎的范围和程度及消化性溃疡发生率与胆汁反流呈正相关。结论胆汁反流是胆石症伴发胃十二指肠疾患的重要因素。
Objective To study the relationship between cholelithiasis and bile reflux in patients with diseases of chronic gastritis and peptic ulcer. Methods The endoscopic and histological changes of gastric and duodenum in 530 patients with cholelithiasis and 100 patients with dyspepsia without cholelithiasis were observed. Results Cholelithosis group had 183 cases of gastric and duodenal diseases (34.5%), of which 98 cases (53.6%) had bile reflux gastritis and 46 cases (25.1%) had peptic ulcer. Cholelithiasis indigestion Groups were 9% and 18% respectively. The extent and degree of chronic gastritis and the incidence of peptic ulcer and bile reflux was positively correlated. Conclusion Bile reflux is an important factor in gallstone disease associated with gastroduodenal diseases.