研究表明 ,端粒酶在人类恶性肿瘤组织中呈高度表达 ,而在正常细胞呈低表达或无表达 ,提示端粒酶表达在恶性肿瘤的发生过程中起着重要的作用。已有报道显示 ,头颈部鳞癌中端粒酶呈普遍表达〔1～ 3〕。然而 ,除少数有关端粒酶在甲状腺腺癌中表达的报道外〔4～6〕,罕见其在头颈部 Studies have shown that telomerase is highly expressed in human malignant tumor tissue, while in normal cells was low expression or no expression, suggesting that telomerase expression plays an important role in the occurrence of malignant tumors. It has been reported that telomerase in head and neck squamous cell carcinoma is generally expressed 〔1 ~ 3〕. However, except for a few reports of telomerase expression in thyroid adenocarcinoma 〔4-6〕, it is rare in the head and neck