常见的促胰岛素分泌剂主要有磺脲类和格列奈类,其中格列奈类药物是目前市面上5大口服降糖药物的一种,也叫做非磺脲类胰岛素促泌剂,临床上代表药物主要有瑞格列奈、那格列奈等,是一种短效制剂。格列奈类药物作用时间短,为餐时血糖调节剂,对空腹血糖起不到明显的治疗效果,较适合于餐后血糖高的患者。以下综述格列奈类药物的应用现状及其研究进展情况。1格列奈类药物的应用研究1.1对高血糖患者的作用机制格列奈类药物主要通过与 Common insulin secretagogues mainly sulfonylureas and glinides, glitterare drugs which are currently on the market five oral hypoglycemic drugs, also known as non-sulfonylurea insulin secretagogue, clinically Representative drugs mainly repaglinide, nateglinide, etc., is a short-acting preparation. Glicerini drugs short acting time, blood glucose regulator for the meal, fasting blood glucose did not achieve significant therapeutic effect, more suitable for patients with high postprandial blood glucose. The following reviews the current status of glinazones and their research progress. 1 glinazac Drugs 1.1 The mechanism of action in patients with hyperglycemia Glinazones mainly through the