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目的 探讨经皮穿刺瘤体内植入12 5I粒子对肺癌进行近距离放疗的效果 ,并对其并发症进行分析。方法 2 0例周围型肺癌患者 ,在模拟定位机或CT定位下 ,通过穿刺针将12 5I粒子植入到肺癌病灶内 ,通过影像学检查观察疗效 ,并观察其并发症。结果 本组 2 0例患者观察 2个月以上者 18例 ,其中CR 2 7.8% (5 / 18) ,PR 6 6 .7% (12 / 18) ,NC 5 .6 % (1/ 18) ,近期有效率 (CR +PR)高达 94 .4 % (17/ 18)。并发气胸 2 0 % (4/ 2 0 ) ,咯少量血痰 2 5 % (5 / 2 0 ) ,胸膜腔内明显出血 5 % (1/ 2 0 ) ,粒子脱入胸膜腔 5 % (1/2 0 )。结论 经皮穿刺瘤体内植入12 5I粒子治疗肺癌有效率高 ,不良反应少而轻
Objective To investigate the effect of brachytherapy on lung cancer with 125I seeds implanted in percutaneous neoplasm and to analyze its complications. Methods Twenty-two patients with peripheral lung cancer underwent lung cancer implantation through a puncture needle under the simulated positioning machine or CT. The therapeutic effect was observed by imaging examination and the complications were observed. Results There were 18 cases of 2 months or more in this group, of which 7.8% (5/18) were CR 2, 6.7% (12/18), 5.6% Recent efficiency (CR + PR) as high as 94.4% (17/18). The pneumothorax was 20% (4/20), slightly sputum 25% (5/20), pleural cavity was significantly bleeding 5% (1/2 0), the particles into the pleural cavity 5% (1/2 0). Conclusion Percutaneous implantation of 125I seeds in vivo for the treatment of lung cancer has high efficiency and few adverse reactions