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血清唾液酸(SA)为癌症标记物之一,已应用于癌症的早期诊断、疗效追踪观察。本文测定40例白血病患者在治疗前后的血清唾液酸水平的动态变化,并以健康献血者40例做对照。对其与病情演变关系作初步探讨。 1 材料和方法 1.1 病例选择:40例均为住院患者,经血髓象检查及细胞组织化学染色确诊,其中男25例,女15例,年龄15～63岁。急性淋巴细胞白血病(ALL)14例(L_12例,L_212例),急性非淋巴细胞白血病(ANLL)18例(M_11例,M_26例,M_32例,M_57例,M_62
Serum sialic acid (SA) is one of the cancer markers and has been used in the early diagnosis of cancer and follow-up of efficacy. This study measured the dynamic changes of serum sialic acid levels in 40 patients with leukemia before and after treatment, and compared 40 healthy blood donors. A preliminary discussion of its relationship with the evolution of the disease. 1 Materials and methods 1.1 Case selection: 40 patients were hospitalized patients, diagnosed by blood myeloid examination and histochemical staining, including 25 males and 15 females, aged 15-63 years. Acute lymphoblastic leukemia (ALL) in 14 patients (L_12, L_212) and acute non-lymphocytic leukemia (ANLL) in 18 (M_11, M_26, M_32, M_57, M_62