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目的观察丁苯酞软胶囊联合依达拉奉注射液治疗进展性脑梗死的临床效果。方法将医院确诊为进展性脑梗死患者120例,随机分为对照组和观察组,每组60例。对照组采用依达拉奉为主的内科综合治疗,观察组在对照组基础上加用丁苯酞软胶囊口服治疗。对2组患者治疗前、治疗2周及4周后神经功能缺损程度、日常生活能力进行比较,对临床疗效进行评价。结果观察组总有效率为93.3%,高于对照组的86.7%(P<0.05);治疗2周、4周后,观察组NIHSS评分值低于对照组(P<0.05),ADL评分值高于对照组(P<0.05)。结论丁苯酞软胶囊联合依达拉奉注射液治疗进展性脑梗死起效快、疗效可靠,可明显改善患者神经功能的缺损和日常生活能力。
Objective To observe the clinical effect of butylphthalide soft capsule combined with edaravone injection in treating progressive cerebral infarction. Methods The hospital was diagnosed as progressive cerebral infarction in 120 patients, were randomly divided into control group and observation group, 60 cases in each group. The control group with Edaravone based comprehensive medical treatment, the observation group on the basis of the control group with butylphthalide soft capsule oral treatment. Two groups of patients before treatment, after treatment for 2 weeks and 4 weeks after the degree of neurological deficit, daily living capacity were compared to evaluate the clinical efficacy. Results The total effective rate in the observation group was 93.3%, which was higher than that in the control group (86.7%, P <0.05). After 2 weeks and 4 weeks of treatment, the NIHSS score of the observation group was lower than that of the control group (P <0.05) In the control group (P <0.05). Conclusion Butylphthalide soft capsule combined with edaravone injection in the treatment of progressive cerebral infarction with rapid onset and reliable curative effect can significantly improve the patients with neurological deficits and daily living ability.