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目的探讨局部应用艾洛松软膏治疗糜烂型口腔扁平苔癣(OLP)的效果。方法选取糜烂型OLP患者30例,用棉签蘸艾洛松乳膏涂于OLP患处,连续用药4周,观察治疗效果。结果治疗2周后,患者疼痛显著减轻,充血及糜烂面积缩小,与治疗前比较,差异有统计学意义(P<0.05)。治疗4周后,上述三项指标减轻明显;治疗期间未出现严重不良反应。30例患者治疗4周后,显效22例(73.33%),有效8例(16.67%)。结论局部应用艾洛松软膏治疗糜烂型OLP临床效果好。
Objective To investigate the effect of local application of Ai Luosong ointment in the treatment of erosive oral lichen planus (OLP). Methods Thirty patients with erosive OLP were selected and treated with cotton swab dipped in Aloxacin cream on the affected area of OLP for 4 weeks. The therapeutic effect was observed. Results After 2 weeks of treatment, the patients’ pain was relieved and the areas of congestion and erosion were reduced. Compared with those before treatment, the difference was statistically significant (P <0.05). After 4 weeks of treatment, the above three indexes were relieved significantly; no serious adverse reaction occurred during the treatment. After 30 weeks of treatment, 22 cases (73.33%) were markedly effective and 8 cases (16.67%) were effective. Conclusion Local application of Ai Luosong ointment for the treatment of erosive OLP clinical effect.