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转化生长因子－β（ＴＧＦ－β）对表达其受体的正常及肿瘤细胞有抗增殖作用，推测ＴＧＦ－β和／或其受体表达降低将导致头颈鳞癌细胞生长失控，该作者对ＴＧＦ－β亚型及其受体亚型在头颈鳞癌中的表达情况进行了研究。应用免疫组织化学方法研究了头颈鳞癌细胞转化生长因子-β
Transforming growth factor-β (TGF-β) has anti-proliferative effects on normal and tumor cells expressing its receptors. It is speculated that decreased expression of TGF-β and/or its receptors will lead to uncontrolled growth of head and neck squamous cell carcinoma cells. The expression of -β isoforms and their receptor subtypes in head and neck squamous cell carcinomas was studied. Immunohistochemical study of transforming growth factor-β in head and neck squamous cell carcinoma