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乙胺碘呋酮系含有39％碘的苯呋喃衍生物。该药为治疗难治性窒性及室上性心律失常的一种有效药物。近来发现,在长期服用本药患者的血浆中存在一种代谢产物—一脱乙基乙胺碘呋酮。由于对该药的母体-胎儿传递过程和过量碘的副作用还不够了解,故在妊娠期使用此药受到限制。妊娠期出现心房纤颤伴W-P-W综合征是一种潜在的致命性心律失常,由于其血液动力学改变和抗心律失常剂的应用,常可危及胎儿。虽然常用药如奎尼丁、异丙吡胺等防止房颤均有疗效,但对快速的侧支传导
Amiodarone is a benzofuran derivative containing 39% iodine. This medicine is an effective drug for the treatment of refractory asphyxia and supraventricular arrhythmias. Recently found that in the long-term use of the drug’s plasma exists in a metabolite - a-ethylamine amiodarone. Because of the drug’s mother-fetus transfer process and excessive side effects of iodine is not yet understood, so the use of this medicine during pregnancy is limited. Atrial fibrillation during pregnancy with W-P-W syndrome is a potentially fatal arrhythmia that can often be fatal to the fetus due to its hemodynamic changes and use of anti-arrhythmic agents. Although commonly used drugs such as quinidine, clove-dipyridamole and other prevention of atrial fibrillation are effective, but the rapid side branch conduction