论文部分内容阅读
目的:探讨早产儿呼吸机相关性肺炎(VAP)的抗生素治疗。方法:回顾本院2004年1月～2007年1月收住新生儿重症监护病房进行机械通气的50例早产儿的临床资料。结果:呼吸机相关性肺炎(VAP)检出的致病菌中,敏感的抗生素依次为泰能、环丙沙星、头孢哌酮舒巴坦钠,临床实践中普遍对泰能敏感。结论:考虑到早产儿的生理特点、药物的安全性以及经济因素,头孢哌酮舒巴坦钠仍为治疗VAP的首选,环丙沙星治疗VAP效果好,虽然其软骨及关节损害未被证实可以应用,但还是由于各种原因大大限制了在儿科的应用。
Objective: To investigate antibiotic treatment of ventilator associated pneumonia (VAP) in premature infants. Methods: The clinical data of 50 premature infants receiving mechanical ventilation from our neonatal intensive care unit from January 2004 to January 2007 were retrospectively reviewed. Results: Among the pathogens detected by Ventilator-Associated Pneumonia (VAP), the sensitive antibiotics followed by tacrine, ciprofloxacin and cefoperazone-sulbactam sodium were generally sensitive to TET in clinical practice. CONCLUSIONS: Given the physiological characteristics of preterm infants, the safety of the drug and the economic factors, cefoperazone-sulbactam sodium is still the first choice for the treatment of VAP and ciprofloxacin is effective in the treatment of VAP although its cartilage and joint damage have not been demonstrated Can be applied, but still for a variety of reasons greatly limits the application in pediatrics.