1.病例介绍 患者男48岁,主因高血压,冠心病,不稳定心绞痛于1995年8月5日由门诊入院。患者既往对复方新诺明有过敏史。8月11日患者因上呼吸道感染,故给予环丙沙星片0.5g口服,1小时后,患者感到咽部发痒,颜面部及前胸出现荨麻疹,考虑为过敏反应。即刻给予苯海拉明20mg肌注。20分钟后,仍不见好转,继而全身出现片状紫瘢,又给予息斯敏片10mg每日1次口服,3天后以上症状消失。 1. Case description Male 48 years old, mainly due to hypertension, coronary heart disease, unstable angina on August 5, 1995 from the outpatient admission. Patients had a history of allergy to cotrimoxazole. Patients on August 11 due to upper respiratory tract infection, it was given ciprofloxacin tablets 0.5g orally, 1 hour later, the patient felt itchy pharynx, facial and chest urticaria, consider an allergic reaction. Immediate diphenhydramine 20mg intramuscular injection. 20 minutes later, still no improvement, and then the whole body flaky purple scar, and given astemizole tablets 10mg daily oral, 3 days after the above symptoms disappear.