P选择素是粘附分子选择素家族的重要成员之一，是一种相对分子质量为 140 000的膜糖蛋白 [1]。由活化的内皮细胞、血小板表达分泌，并可做为这些细胞活化的标志。有关 P选择素与 SLE的关系报道甚少，为探讨两者之间的关系，我们采用双抗体夹心 ELISA法对 25例 SLE患者血浆 P选 P-selectin is one of the important members of the adhesion molecule-selective family and is a membrane glycoprotein with a relative molecular mass of 140 000 [1]. It is secreted by activated endothelial cells and platelets and serves as a marker for the activation of these cells. There are few reports on the relationship between P-selectin and SLE. To explore the relationship between P-selectin and SLE, we used double antibody sandwich ELISA to detect plasma P