雷尼替丁是继甲氰咪胍后一种新的H_2受体阻滞剂,它作为消化性溃疡的治疗药物已在国内外许多国家广泛应用,但静脉注射Zantac(Ranitidine注射液)治疗急性上消化道出血的经验报告尚不多.为了探讨其疗效及临床应用价值,本文报道了40例急性上消化道出血患者应用英国GLAXO公司生产的Zantac静脉注射的疗效观察.临床资料本组40例.男性28例,女性12例:年龄:24-81岁.临床上均有活动性出血:呕血及或黑便,伴有不同程度头昏,心悸及血压下降。全部病例均经急诊纤维胃镜检查,除3例外.其余37例均确定出血病因及部位(见表1-1).治疗方法以Zantac50mg加入50％葡萄糖20ml静脉推注,继以Zantac150mg加入5％葡萄糖500ml静脉滴注,1次/日,至出血停止,改口服Ranitidine Ranitidine is a new H_2 receptor blocker after cimetidine. It has been widely used in many countries at home and abroad as a therapeutic drug for peptic ulcer. However, intravenous injection of Zantac (Ranitidine Injection) for acute In order to explore its efficacy and clinical value, this article reports the 40 cases of acute upper gastrointestinal bleeding patients using the British company GLAXO intravenous injection of Zantac efficacy of clinical data in this group of 40 patients 28 males and 12 females: Ages: 24-81 years old, with active bleeding in clinical practice: hematemesis and melena, accompanied by varying degrees of dizziness, palpitation and blood pressure drop. All cases were diagnosed by emergency fiberoscopy, with the exception of 3. The remaining 37 cases were identified etiology and site of bleeding (see Table 1-1) .Methods of treatment Zantac50mg 50% glucose 20ml intravenous injection, followed by Zantac150mg added 5% glucose 500ml intravenous infusion, 1 times / day, to stop bleeding, change oral Ranitidine