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肝肠钙黏着蛋白（ LI－cadherin）具有细胞识别、细胞黏附的功能，并在组织器官的神经传导方面起重要作用。 LI－cadherin是现今被发现的多种钙黏着蛋白中的一员，如果 LI－cadherin 的结构和性质发生改变，将导致其细胞黏附等功能出现紊乱，最终组织器官的结构和功能发生障碍。而消化道系统的多种恶性肿瘤中存在着 LI－cadherin 的结构和功能异常。 LI－cadherin可作为消化道肿瘤的一项重要的标志物，对肿瘤的早期诊断及判断预后均有重要的临床意义。“,”Liver-intestine cadherin(LI-cadherin) has cell recognition,cell adhesion function,and plays an important role in nerve conduction of tissues and organs.Now It′s found to be a member of a variety of cadherins.In addition,the changes of structure and nature of LI-cadherin will lead to cell adhesion and other functions disorders,and structure and function disorders of the organ finally.In a variety of malignant tumors in the digestive system,there are structural and functional abnormalities of LI-cadherin.LI-cadherin can be regarded as an important marker of digestive tract tumor ,and has great clinical significance for early diagnosis and prognosis of the tumor.