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为探讨头颈恶性肿瘤组织提取液是否含有聚集血小板的物质,将15例头颈恶性肿瘤和14例非恶性肿瘤组织匀浆取组织提取液,分别致聚于头颈恶性肿瘤21例.非肿瘤、非恶性肿瘤33例及健康人16例的血小板。发现,头颈恶性肿瘤组织提取液致聚的阳性率比非恶性头颈肿瘤组织提取液致聚的高;头颈恶性肿瘤组织提取液对血小板的聚集作用随病期进展而增强;头颈部恶性肿瘤病人的血小板易受组织提取液激聚,其血小板最大聚集率随病期进展而增强。表明,晚期头颈恶性肿瘤组织含促血小板聚集物,这可能是直接引起恶性肿瘤机体血小板聚集增强的原因之一。
In order to investigate whether the extract of head and neck malignant tumor contains platelet-aggregating substance, 15 cases of head and neck malignant tumor and 14 cases of non-malignant tumor tissue homogenate were taken and collected respectively in 21 cases of head and neck malignant tumor.Non-tumor and nonmalignant Tumor in 33 cases and healthy 16 cases of platelets. It was found that the positive rate of aggregation of head and neck malignant tumor tissue extract was higher than that of non-malignant head and neck tumor tissue extract. The aggregation of platelet by the extract of head and neck malignant tumor increased with the progression of the disease. The head and neck malignant tumor patients Of platelets vulnerable to tissue extract exfoliated, the maximum rate of platelet aggregation with the progression of the disease and enhanced. This suggests that advanced head and neck malignant tumor tissue contains platelets aggregates, which may be one of the reasons that the platelet aggregation of malignant tumor directly increases.