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目的探讨C-反应蛋白(CRP)与老年冠心病严重程度的关系,判断老年冠心病患者远期心血管事件发生及预后。方法将125例老年冠心病患者分为CRP正常组和CRP异常组,采用免疫散射比浊法,测定血清CRP浓度。正常组0～6mg/L。所有患者随访1年,比较两组患者不稳定型心绞痛、心肌梗死、心脏猝死发生情况。结果CRP异常组发生心脏事件明显高于CRP正常组。表明CRP水平可作为识别冠心病高危患者鉴别的指标,其异常升高程度与冠状动脉粥样硬化程度有明显相关性,为心血管事件的预测和预后提供依据。
Objective To investigate the relationship between C-reactive protein (CRP) and the severity of coronary heart disease (CHD) in elderly patients and to evaluate the long-term cardiovascular events and prognosis in elderly patients with CHD. Methods 125 cases of elderly patients with coronary heart disease were divided into CRP normal group and CRP abnormal group, and the serum CRP concentration was determined by immune nephelometry. Normal group 0 ~ 6mg / L. All patients were followed up for 1 year. The incidence of unstable angina pectoris, myocardial infarction and sudden cardiac death in both groups were compared. Results The incidence of cardiac events in CRP abnormal group was significantly higher than that in CRP normal group. CRP levels can be used as a marker to identify high-risk patients with coronary heart disease, the abnormal increase in the degree of coronary atherosclerosis with a significant correlation, and provide a basis for the prediction and prognosis of cardiovascular events.