该院口腔颌面外科肿瘤生物实验室完成的一项研究证实,人乳头状瘤病毒(HPV)感染可诱发 口腔鳞癌。不久前,该成果通过了上海市科委组织的专家鉴定。专家认为,该研究达到国际先进水平,部分研究达国际领先水平。 口腔鳞癌恶性程度很高,好发于口腔粘膜。除吸烟、饮酒和不良修复体长期刺激等因素外,HPV感染是否还与口腔鳞癌发生有关,一直是世界医学界悬而未决的难题。为此,由该院口腔颌面外科主任张志愿教授领衔,帕地曼博士等研究人员经3年潜心研究,在国内率先建立了永生化口腔上皮细胞系。他们以该细 A study done by the Oral and Maxillofacial Surgery Tumor Biology Laboratory confirmed that human papillomavirus (HPV) infection can induce oral squamous cell carcinoma. Not long ago, this achievement passed the expert appraisal organized by Shanghai Science and Technology Commission. Experts believe that the study reached the international advanced level, some of the research reached the international advanced level. Oral squamous cell carcinoma of the high degree, occur in the oral mucosa. In addition to smoking, drinking and long-term stimulation of prosthetic and other factors, the HPV infection is also associated with the occurrence of oral squamous cell carcinoma, has been the world's medical community in unresolved problems. To this end, led by Professor Zhang Zhiyuan, director of Oral and Maxillofacial Surgery in the hospital, Dr. Paderman and other researchers after three years of painstaking research, the first to establish an immortalized oral epithelial cell line in China. They are fine