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目的通过分析1例肺癌病例化疗期间并发严重低钠血症反应的诊疗不合理因素,总结防治肿瘤治疗并发症的药学监护要点,培养临床药师诊断和监护常见副肿瘤综合征的能力。方法参照临床诊治指南,结合患者病史、辅助检查及治疗经过等情况,从诊断、病因、治疗计划及药物选择方面,逐一分析低血钠并发症的诊治不利因素和不当措施,阐述临床药师在各环节中应采取的合理监护措施,归纳有效防治抗利尿激素异常分泌综合征的药学监护要点。结果经过后期的密切监护,患者并发症反应缓解并顺利完成化疗;临床药师掌握了肿瘤患者抗利尿激素异常分泌综合征的诊治知识和监护方法。结论临床药师应注重积累和总结临床监护经验,尽早介入诊疗,全程跟进病程,才能真正有效地发挥自身价值。
Objective To analyze the unreasonable factors of the diagnosis and treatment of severe hyponatremia reaction during chemotherapy in a case of lung cancer, summarize the points of pharmaceutical care for preventing and treating the complications of cancer treatment, and train clinical pharmacists to diagnose and monitor common paraneoplastic syndromes. Methods According to the clinical diagnosis and treatment guidelines, combined with the patient’s medical history, auxiliary examination and treatment, etc., from the aspects of diagnosis, etiology, treatment plan and drug selection, analyze the unfavorable factors of diagnosis and treatment of hyponatremia and inappropriate measures, and elaborate the clinical pharmacists in each The reasonable guardianship measures that should be taken in the link should summarize the points of effective pharmaceutical control for the prevention and treatment of antidiuretic hormone abnormal secretion syndrome. Results After close monitoring, patients’ complications were relieved and chemotherapy was successfully completed. The clinical pharmacist mastered the diagnosis and treatment of antidiuretic hormone abnormal secretion syndrome in tumor patients. Conclusions Clinical pharmacists should pay attention to accumulating and summarizing clinical custodial experience, intervene in diagnosis and treatment as soon as possible, and follow up the course of the disease in order to truly realize their value.